Building upon the original goals of the BWF Preterm Birth Initiative, a recently convened Pregnancy Think Tank has helped shape the next iteration of this award mechanism. Growing evidence suggests the interrelatedness of the duration of pregnancy, fetal growth, and adverse pregnancy outcomes such as preterm birth, preeclampsia, intrauterine growth restriction, stillbirth, and maternal medical complications including maternal mortality. Other areas of interest are climate change and environmental impact on pregnancy, complications associated with ART, and epigenome-wide association studies. BWF has expanded the scope of this award mechanism to capture these and other pregnancy outcomes as BWF believes they will be mutually informative and accelerate discovery.
For additional background information, see: https://www.bwfund.org/wp-content/uploads/2020/10/BWF-NGPI-RFP-2024_v3.pdf#page=3
Proposals should address the biomedical causes and molecular mechanisms underlying adverse pregnancies and their outcomes including but not limited to peri-implantational events, placentation, fetal determinants, fetal-maternal immune responses, biological basis for racial-ethnic disparities, mechanisms relating preterm birth to other adverse pregnancy outcomes, biology of normal labor, genomics, evolutionary influences, maternal complications and other approaches. Proposals seeking to identify biomarkers predicting preterm birth are welcome.
BWF is also interested in Preterm Birth Risk Stratification using artificial intelligence and machine learning. Proposals that cross institutional boundaries (partnerships between multiple universities or collaborations within larger universities) are welcomed.
The support allocated for research is under the control of the principal investigator and may be used flexibly for items such as equipment, consumable supplies, travel to scientific meetings, and laboratory personnel working with the principal investigator. Prior approval by BWF is required when, within an award year, purchases of equipment exceed $20,000 or travel costs exceed $8,000.